Investigation of changes in serum thiols and neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume/platelet count ratio indices in cats undergoing ovariohysterectomy
Investigation of changes in serum thiols and neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume/platelet count ratio indices in cats undergoing ovariohysterectomy
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The aim of this study was to investigate complete blood indices [neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume/platelet count ratio (MPV/PLT)] and thiols (native and thiol) in cats undergoing ovariohysterectomy (OHE).The study sample comprised a total of 10 female cats of mixed breeds.Ovariohysterectomy operation was performed under Ketamine/Xylazine anesthesia with the appropriate technique.
Blood gruvi golden lager samples were collected from the cephalic vein pre-OHE and post-OHE at 2 h, 24 h, and 7 d.Total and native thiol levels in the serum were analyzed using a colorimetric technique, and whole blood analysis was carried out using anticoagulant tubes.White Blood Cell (WBC) and neutrophil increased significantly at 2 h post-OHE, peaked at 24 h post-OHE, then returned to baseline levels by 7 d (P<0.
001).The lymphocyte and thiols decreased at 2 h, 24 h, and 7 d post-OHE, and the lowest lymphocyte count was observed at 24 h (P<0.001).
The lowest monocyte count was observed on d 7 post-OHE (P<0.001).NLR increased significantly 2 h after OHE, peaked at 24 h after OHE, incredibleindiatourtravels.com and remained high on d 7 (P<0.
001).MLR increased at 2 h, peaked at 24 h, then returned to baseline levels on d 7 (P<0.001).
PLR increased gradually and peaked at 24 h and on d 7 (P<0.001).MPV/PLT after OHE was statistically lowest on d 7 (P<0.
05).A negative correlation was determined between NLR, MLR, PLR, and thiols (P<0.001).
In conclusion, thiols and complete blood indices (NLR, MLR, and PLR) may be important in the assessment of inflammation and stress responses after OHE in cats.